摘要
采用薄膜蒸发法制备薯蓣皂苷元纳米脂质体,通过优化溶剂种类、表面活性剂种类、乳化和匀质条件等,确定最佳制备条件。结果表明,薯蓣皂苷元纳米脂质体的最佳制备技术为:以乙醚为溶剂,胆酸钠为表面活性剂,较高的乳化转速,700bar高压匀质。
Nanometer diosgenin liposome was prepared by using thin film evaporation and the optimum preparation condition was confirmed through optimizing solvent type,surfactant species,emulsification and homogenization condition.The results indicated that the optimum prepa-ration technology of nanometer diosgenin liposome was preparation with aether as solvent,sodium cholate as surfactant and through emulsifica-tion at higher rotation speed and homogenization under high pressure of 700 bar.
出处
《安徽农业科学》
CAS
北大核心
2010年第28期15454-15456,共3页
Journal of Anhui Agricultural Sciences
基金
国家"十一五"科技支撑项目(2006BAB04A14)
四川省科技支撑项目(2008SZ2004)
关键词
薯蓣皂苷元
脂质体
薄膜蒸发法
制备技术
Diosgenin
Liposome
Thin film evaporation
Preparation technology