摘要
目的对香菇多糖口腔膜剂的制备工艺进行研究,并筛选出最佳处方。方法先对预实验得出的处方进行筛选,再以黏附力、溶解性作为评价指标进行综合评价,筛选出最佳膜剂配方。结果通过对各配方比较得出最佳配方:聚乙烯醇3.6g,羧甲基纤维素钠0.4g,甘油0.5ml。结论根据最佳处方制备的口腔膜剂,在黏附性、溶解性方面符合要求,而且外观也比较理想。
Objective To investigate the method for preparation of Lentinan oral film and select the best formula. Methods By selecting the pre - test prescription,the best formula was finally determined on the basis of characteristics of eonglution and dissolution. Resuits The results showed that the optimalizing formula of the oral film which was made of polyvinyl alcohol 3.6g,sodium carboxymethyl cellulose 0.4g,glycerin 0.5ml was choosed by conglutination and dissolution. Conclusion The oral film designed according to the optimalizing formula coincided with the requirements in conglutination and dissolution,and its appearance was perfect.
出处
《医学研究杂志》
2010年第10期115-118,共4页
Journal of Medical Research
