摘要
目的探讨早期乳腺癌保乳手术术中电子线照射的可行性及近期效果。方法 36例早期乳腺癌患者接受保乳手术+术中放疗(A组),使用9Mev电子线21Gy一次照射;另41例患者接受术后全乳照射(B组),剂量为50～60Gy/5～6周(全乳50Gy,瘤床加量至60Gy),比较两组放疗时间及费用、毒副反应、美容效果、肿瘤复发事件、手术及伤口愈合时间等。结果与B组相比,A组放疗时间短[(3～5min×1次)vs.3～5min×(25～30)次)]、费用少[(3300±135)元vs.(13800±566)元]、形体满意度佳(97.2%vs.87.8%)、毒副反应少,而手术时间[(128±18)minvs.(94±12)min]和切口愈合时间[(13.8±2.4)dvs.(8.1±1.8)d]延长。结论保乳手术术中放疗具有省时、省钱、照射部位确切、美容效果佳、毒副反应小等特点。
Objective To evaluate the feasibility and short-term efficacy of breast-conserving surgery with intraoperative radiotherapy in patients with early-stage invasive breast cancer.MethodsThirty-six patients（group A） with early-stage invasive breast cancer received intraoperative radiotherapy with 21 Gy electrons at 9 Mev and other 41 patients（group B） received conventional postoperative whole-breast radiotherapy after breast-conserving surgery.The time,cost and toxicity of radiotherapy,comestic results,recurrence and metastasis events,time of operation and wound healing were compared.Results Compared with group B,group A was with shorter time（3-5 min for 1 time vs.3-5 min for 25-30 times） and less money ／[（3300±135） yuan vs.（13 800±566） yuan／],better body satisfaction （97.2% vs. 87.8%） and less side effects,but with longer time for operation／[（128±18） min vs.（94±12） min／] and for wound healing／[（13.8±2.4） d vs.（8.1±1.8） d／].Conclusion The intraoperative radiotherapy after breast-conserving surgery has the advantages of lower cost,shorter time,accurate dose delivery,good comestic results and protection of adjacent tissues.
出处
《江苏医药》
CAS
CSCD
北大核心
2010年第18期2173-2175,共3页
Jiangsu Medical Journal
关键词
术中放疗
保乳手术
Intraoperative radiotherapy
Breast-conserving surgery
