摘要
目的:分析多发性肌炎(PM)和皮肌炎(DM)的临床特征。方法:对70例多发性肌炎和皮肌炎患者的临床资料、实验室检查、治疗及转归进行回顾性分析。结果:本组男女之比为1:1.87,发病年龄13～81岁,平均51.52岁。58例皮肌炎患者以皮肤症状为首发症状者占62%,皮肤损害中以双上眼睑紫红斑最多,占70%。乳酸脱氢酶(LDH)和肌酸磷酸激酶(CPK)阳性率分别为74.3%和51.4%,抗Jo-1抗体阳性率为1.4%。肌活检肌炎性和肌电图肌源性改变分别为90%和56.9%。恶性肿瘤伴发率约为12.9%。结论:45岁以上的患者要注意对恶性肿瘤的筛查。
Objective： To characterize clinical features of polymyositis （PM） and dermatomyositis （DM）. Methods： The clinical and laboratory data of 70 cases with DM/PM were analyzed retrospectively. Results： The ratio of male to female was 1：1.87, and the age at onset ranged from 13 to 81 years （mean： 51.52 years）. Out of 58 DM patients, skin lesion as the first symptom accounted for 62% of the patients, of which erythema in palpebra frontalis was seen in 70% of these patients. The level of LDH and CPK was increased in 74.3% and 51.4% of the patients respectively. The positivity rate of anti - jo - 1 antibody was 1.42%. Muscle biopsy showed abnormality in 90% of the patients, and EMG showed 56.9% of the patients having myogenous change. The malignant tumor was 12.9% in the group of patients. Conclusion： Screening of malignancy should be taken in the patients aged above 45 years.
出处
《中国麻风皮肤病杂志》
2010年第10期697-699,共3页
China Journal of Leprosy and Skin Diseases
关键词
多发性肌炎
皮肌炎
polymyositis
dermatomyositis
