摘要
目的:研究石见穿的化学成分。方法:利用系统溶剂提取法、正相和反相硅胶柱色谱法、制备HLPC法经进行分离和纯化,采用谱学技术(NMR谱,MS,UV等)进行结构鉴定。结果:从石见穿醋酸乙酯部位分离得到3,5,7-三羟基色原酮(Ⅰ),山柰酚(Ⅱ),5,7,4′-三羟基二氢黄酮醇(Ⅲ),3,5-二甲氧基-4-羟基安息香酸(Ⅳ)及丁香脂素(Ⅴ)5个化合物。结论:化合物Ⅲ～Ⅴ是首次从该植物分离得到。
OBJECTIVE To Study on the chemical constituents in the cane part of Salvia chinensis Benth. METHODS The compounds were isolated by the solvent extraction , silica gel , and reversed-phase silica gel column chromatography and semipreparative HLPC chromatography. The structures were identified by various spectroscopic methods including NMR spectrum, MS, UV, etc. RESULTS Five aromatic compounds were isolated and purified from the ethyl acetate fraction and identified as 3, 5,7-trihydrochromone （ I ）, kaempferol （ II）, 5,7,4＇-trihydroxydihy-droflavonol （ III ）, 3, 5-dimethoxy-4-hydroxybenzoic acid. （IV）, syringaresinol （ V ）. CONCLUSION Compouds 3-5were obtained from the plant for the first time.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2010年第19期1657-1660,共4页
Chinese Journal of Hospital Pharmacy
基金
武汉市晨光计划项目(编号:SZY09005)资助
关键词
石见穿
醋酸乙酯部位
化合物
Salvia chinensis Benth
ethyl acetate fraction
chemical constituents
