期刊文献+

NDV对体外培养的肿瘤细胞杀伤性研究 被引量:6

Study on the killing function of NDV to cultured tumor cells in vitro
暂未订购
导出
摘要 目的:探讨NDV病毒体外对肿瘤细胞的杀伤性。方法:人的SGC-9701和SMMC-7721肿瘤细胞为靶细胞,观察了NDV对其直接杀伤作用。结果:NDV病毒能作用于瘤细胞,并最终使肿瘤细胞死亡。结论:NDV病毒是一种有效的肿瘤细胞溶解剂,在体外具有明显的直接杀伤瘤细胞作用。 Purpose: To probe into the killing function of Newcastle disease virus(NDV) to cultured tumor cells in vitro. Methods:Human SGC-9701 and SMMC-7721 tumor cells were regarded as target cells to observe the direct killing effect of NDV on them. Results:5BZNDV had an effect on tumor cells and finally made them dead. Conclusion: NDV might be an effective dissolvent to tumor cells.It has obvious direct killing effect on tumor cells in vitro.
出处 《西北国防医学杂志》 CAS 1999年第2期103-104,共2页 Medical Journal of National Defending Forces in Northwest China
关键词 新城疫病毒 细胞培养 肿瘤细胞杀伤性 Neoplasfic therapy Newcastle disease virus Cell culture
  • 相关文献

参考文献1

二级参考文献1

共引文献1

同被引文献44

  • 1Reichant KW, Lorence RM, Cascine CJ, et al. Newcastle disease virus selectively kill human tumor cells[J]. J Surg Res, 1992,52 : 448-453.
  • 2Noteborn MHM, de Boer GF, vou Roozelar DJ, et al. Characterization of cloned chicken anemia virus DNA that contain all elements for the infectious replication cycle[J]. J Virol, 1991, 65(8) : 3131-3139.
  • 3Noteborn MHM, Todd D, Verschueren CA J, et al. A single chicken anemia virus protein induce apoptosis[J]. J Virol, 1994,(68) : 346-351.
  • 4Chen SH, Kosai K, Xu B, et al. Combination suicide and cytokine gene therapy for hepatic metastases of colon carcinoma: Sustained antitumor immunity prolongs animal survival [J]. Cancer Res, 1996,56 : 3758-3762.
  • 5Putzer BM, Bramson JL, Addison CL, et al. Combination therapy with interleukin-2 and wild-type p53 expressed by adenoviral vectors potentiates tumor regression in a murine model of breast cancer[J]. Hum Gene Ther, 1998, 9: 707-718.
  • 6Hall PA, Levision DA. Assessment of cell proliferation in histological material[J]. J Clin Pathol, 1990, 43: 184-197.
  • 7Reichard KW, Lorence RM, Cassino CJ, et al. Selective replication of Newcastle disease virus(NDV) in cancer cells is associated with virus-induced cell fusion [ J ]. Proc Am Assoc Cancer Res,1992, 33 : 521-525.
  • 8PhuangsabA,LorenceRM,ReichardKWetal. Newcastle disease virus therapy of human tumor xenografts: antitumor effects of local or systemic administration[ J ]. Cancer Lett,2001; 172(1 ) ;27
  • 9Wildner O. Oncolytic viruses as therapeutic agents[J]. Ann Med,2001 ;33 (5) :291
  • 10Prigent P, Blsnpied C, Aten J et al. A safe and rapid method for analyzing apoposis induced fiagmentation of DNA extracted from tissues or cultured cells[J]. J I mmunolgoical Methods, 1993; 160:139

引证文献6

二级引证文献26

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部