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高血压病患者右心室结构和功能的变化及相关因素分析 被引量:8

Changes of right ventricular structures and functions in hypertensive patients and analysis of related factors
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摘要 本文研究高血压病患者右心室结构和功能变化、影响因素及其与左室结构和功能变化的关系。分析89例未经治疗的Ⅰ或Ⅱ期高血压病患者与82例正常对照者之间按超声心动图测算的右室解剖结构和功能指标的差异、相关关系及其与左室对应指标及其他影响因素的相关性。结果显示:高血压病患者右室前壁厚度增加,舒张期充盈受损,经协方差分析将年龄、性别、体重指数及心率等的影响剔除之后,差异仍存在显著性。收缩功能指标无显著性变化。右室结构和功能变化与血压水平和高血压所致的左室结构和功能变化之间有显著性相关关系。年龄、性别、体重指数及心率也是影响右室结构和功能测值的可能因素。 The study was carried out to investigate the changes of right ventricular structures,functions, and their associations with related factors and with the changes of indices of left ventricular structures and functions in hypertensive patients Indices of the right ventricular structures and functions measured and calculated by echocardiographic method in eighty nine untreated patients with essential hypertension of or stage and eighty two normotensive control subjects were studied The differences of the indices between hypertensive and normotensive groups were compared and correlations of the indices of right ventricular structures and functions with related factors and with the indices of left ventricular structures and functions were analysed Results showed that the thickness of right ventricular anterior wall increased and right ventricular diastolic filling function decreased The differences of the indices of right ventricular structures and functions between the hypertensive and normotensive groups were statistically significant which persisted even after adjusted for age,sex,body mass index(BMI) and heart rate (HR) by covariance analysis No significant changes of the indices of right ventricular contractile function were found in hypertensive patients It was found that statistically significant correlations existed between the changes of indices of right and left ventricular structures and functions Besides the level of blood pressure and extent of hypertensive changes of left ventricular structures and functions, age, sex, BMI and HR were factors affecting the indices of right ventricular structures and functions too
出处 《心功能杂志》 1999年第2期91-94,共4页
关键词 高血压病 右心室 结构 功能 相关因素 hypertensionright ventricular structure and function
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