摘要
目的:探讨RF分型在类风湿关节炎中的临床应用。方法:ELISA法。结果:①ESR升高的患者中血清各型RF浓度显著高于ESR正常的RA患者。且ESR正常的RA患者血清各型RF浓度也明显高于健康人群;②ESR升高的活动期RA患者,治疗后ESR转为正常期血清中各型RF的变化,结果显示各型RF都有明显降低,尤以IgG-RF降低更为突出(P<0.01)。结论:尽管ESR是一种判定RA炎症活动度和病情缓解的可靠指标,但特异性不强,且阳性率不高,而测定血清各型RF更能反映患者病情状况;并能对临床治疗效果、患者恢复程度及预后做出判断。
Objective： So as to explore the clinical significance of RF categories in RA. Methods： ELISA method. Results： ①Each FR type density of ESR positive patients is notably higher than not only ESR negotive patients but also normal persons,and Each FR type concentration of ESR negotive patients is remarkably higher than normal control too via statistic analysis（P〈0. 01） . ②Each FR type density from ESR positive patients to ESR negotive patients through treatment is lower（P〈0. 01） . Conclusions： There are high sensitivity and speciality by surveying Each FR type in rheumatoid arthritis,so there are important clinical significance in improving diagnostic rate、judging disease situation and evaluating curative effect,
出处
《航空航天医药》
2010年第9期1573-1574,共2页
Aerospace Medicine
