摘要
目的探讨高同型半胱氨酸血症与2型糖尿病肾病的关系。方法将100例T2DM患者按DN诊断标准分为DN组与非肾病(NDN)组。另择52例健康人作为健康对照(NC)组。同时检测3组的尿微量清蛋白排泄率(UAER)、糖化血红蛋白(HbA1c)、肌酐(Cr)、尿素氮(BUN)、同型半胱氨酸(Hcy),进行相关的统计学分析。结果 3组HbA1c、Cr、BUN、UAER、Hcy值比较差异有统计学意义(P<0.01)。Hcy与UAER、Cr、BUN、HbA1c呈明显的正相关,与UAER相关性显著。结论高同型半胱氨酸血症是糖尿病肾病的一个重要危险因素。
Objective To explore the relationship between Hyperhomocysteinemia and diabetic nephropathy（DN）.Methods 100 patients with suspected DN were devided into three groups according to detection：DN、NDNgroup and control group.The patients serum HbA1c,Hcy,BUN,Cr,UAER were detected by the standard method.Results HbA1c,Hcy,BUN,Cr,UAER level was elevated significantly in DN group（P0.01）,and HbA1c,Hcy,BUN,Cr,UAER have statistical difference and relevance among the three groups.Conclusion Hyperhomocysteinemia was an independent risk factor in DN.
出处
《检验医学与临床》
CAS
2010年第19期2089-2089,2146,共2页
Laboratory Medicine and Clinic
