摘要
目的评价射频消融(RFA)与肝动脉栓塞化疗(TACE)对肝癌的疗效和副反应。方法对65例肝癌患者,随机分成RFA治疗组30例及TACE治疗组35例,术后观察病人的主要临床症状、AFP及肝功能变化、B超和CT检查结果。结果 RFA治疗组,肿块直径<5cm者的完全消融(complete ablation,CA)率为86.96%(20/23),>5cm者为20.59%(7/34),其中>10cm的均为不完全消融或部分消融;射频后大多数患者症状明显改善;副反应包括术中疼痛、恶心和术后出现发烧、转氨酶升高等。TACE治疗组:肿块的碘油沉积大部分低于50%,且复发率较高,常见副反应有发热、骨髓抑制、消化道反应。结论 RFA、TACE在治疗肝癌上是安全、有效的方法,但应慎重进行。
Objective To evaluate the therapeutic effect and adverse effects of radio frequency ablation （RFA） and transcatheter arterial ehemoembolization（TACE） for the treament of live cancer. Methods In this study,30 patients underwent RFA and 35 patients underwent TACE. After treatment, the main symptoms, AFP level and live function were observed. Meanwhile, ultrasonography and CT scanning were performed. Results RFA： The complete ablation（CA） rate was 86. 96% （20/23） in tumors less than 5 cm in diameter, and 20. 59% （7/34） when tumors were larger than 5 cm,the partially or uncompletely ablation in tumors larger than 10 cm, signs of toxicity included pain during operation,nausea fever after operation, transaminase elevation and so on. TACE： lipiodol deposition 〈 50% in part cases; signs of toxicity included fever, myelosuppression, gastrointestinal tract reaction. Conclusion Treating liver cancer by RFA and TACE is effective and safe,but great care should be taken.
出处
《中国临床新医学》
2010年第9期823-826,共4页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
基金
贺州市科技局立项课题(编号:0520020)
关键词
肝癌
射频消融
肝动脉栓塞化疗
Liver cancer
Radiofrequency ablation
Transcatheter arterial chemoembolization
