摘要
肝细胞性肝癌(hepatocellular carcinoma,HCC)在我国高发,对部分有高危复发因素的患者肝切除手术仍作为首选的治疗方式,然而此部分患者术后的复发率较高,需要采取多种手段降低术后复发率.然而术后单一的复发预防方法有其局限性,应该在熟悉多种治疗方式疗效的基础上强调术后综合治疗.本文结合肝癌术后复发起源及分子机制,就有高危复发因素肝癌术后复发预防的相关治疗方式进行阐述,探索更为合理有效的综合治疗方案对防治有高危复发因素的肝癌患者术后复发具有重要意义.
The incidence of hepatocellular carcinoma （HCC） is high in China. Hepatectomy is the first choice for some HCC patients at a high risk of recurrence; however, the rate of postoperative recurrence in these patients remains high. Since single postoperative treatment trying to avoid recurrence often does not work effectively, more than one means are needed to reduce the recurrence on the basis of understanding the effectiveness of different therapeutic methods. In this paper, we will discuss the origin and molecular mechanisms of recurrence as well as the related treatments for HCC at a high risk of recurrence, with an aim to explore more effective and reasonable comprehensive treatments to prevent recurrence in HCC patients at a high risk of recurrence after hepatectomy.
出处
《世界华人消化杂志》
CAS
北大核心
2013年第30期3183-3189,共7页
World Chinese Journal of Digestology
基金
2011年度安徽省科技攻关基金资助项目
No.11010402163~~
关键词
肝细胞性肝癌
肝动脉化疗栓塞
索拉非尼
干扰素
化疗
维生素
Hepatocellular carcinoma
Transcatheter arterial chemoembolization
Sorafenib
Interferon
Chemotherapy
Vitamin
