摘要
用人类红白血病细胞（Ｋ５６２）为材料，通过细胞计数、ＭＴＴ法测定，形态学观察、ＮＢＴ还原试验及联苯胺反应等方法检测了不同浓度姜黄素对体外人Ｋ５６２细胞的作用。结果表明，姜黄素对Ｋ５６２细胞有明显的抑制作用，随浓度增加，抑制作用逐渐增强。形态学观察可见轻微诱导分化作用。鉴于姜黄素对人类红白血病细胞兼有轻微诱导分化和增殖抑制作用，提示姜黄素有可能应用于人类红白血病的治疗。
In vitro effrcts of different concentration of curcumin has been studied on the K 562 cells(human erythrocytic leukemic cells)with methods of cell counting,MTT,morphology and Benzdine reaction.Results showed that curcumin had significant inhibition effect on K 562 with dose dependent character.Slight differentiation induction was observed morphologially.It is therefore indicated that curcumin may be used in the treatment of human erythrocytic leukemia.
出处
《大连医科大学学报》
CAS
1999年第2期98-100,共3页
Journal of Dalian Medical University
