摘要
目的:研究金丝桃甙(Hyp)对神经组织Ca^（2+）含量的影响。方法:游离的蛙坐骨神经Ca^（2+）含量用原予分光光度仪测定。结果;Hypl×l0^(-5),1×10^(-6)和1×10^(-7)mol.L^(-1)显著并呈浓度依赖性抑制50mmol,L^(-1)K^+诱导Ca^(2+)含量增加,1×10^(-4)mol.L^(-1)Hyp显著抑制10^(-5)mo1.L^(-1)NE诱导的Ca^(2+)含量增加。结论:Hyp对神经组织Ca^(2+)内流有阻滞作用。
OBJECTIVE:To study the effect of Hyperin (Hyp. ) on calcium ion content in ver-vous tissue. METHOD: Calcium ion content in the isolated sciatic nerve of frog was measured with atomic absorption spectrophotometer. RESULTS: Hyp.1×10-5,1×10-6,and 1×10-7mol L-1markedly inhibited.the increase of Ca2+content evoked by K+50 mmol. L-1 in a concentration depentent manner. Hyp: 10-4mol ?1L-1 inhibited the increace of Ca+2 content induced by NE 10-5 mol. L-1. CONCLUSION: Hyp. had inhibitory effect on influx of Ca2+ in nervous tissue.
出处
《基层中药杂志》
1999年第2期16-17,共2页
Primary Journal of Chinese Materia Medica
