摘要
目的：研究改良治疗方案治疗急性有机磷农药中毒的可行性及其临床应用价值。方法：８２例中毒患者根据临床症状、体征、血清胆碱酯酶活性（ＣｈＥ）将中毒程度分为轻、中、重度３级，分别采用改良治疗方案（将阿托品与解磷注射液配伍成的具有规范化、阶梯序贯式用药），与我科既往按传统方案治疗的８１例有机磷农药中毒患者进行对照比较。结果：改良疗法组治愈７９例，显著高于传统疗法组（治愈６１例，Ｐ＜０．０５），而阿托品中毒率及农药中毒反跳率、阿托品用量及住院时间均低于传统用药组，具有显著性（Ｐ＜０．０５）或高度显著性差异（Ｐ＜０．００１）。结论：改良治疗方案救治急性有机磷农药中毒疗效显著。
Objective:To evaluate the possibility and the clinical value of the improved regimen in the treatment of acute organophosphorus pesticide poisoning.Methods:According to clinical symptoms,signs,and serum cholinesterase activity,82 cases with acute poisoning were divided into mild,moderate,as well as severe group.They were treated by the improved treatment regimen comprising of atropine and Jielin Injection(解磷注射液) administered in a standardized and programed way.The results were compared with 81 cases treated with traditional regimen.Results:The cure rate of the improvement design was significantly higher than that of the traditional method (79/82 vs.61/81 cases, P <0 05).Also,the incidence of atropine poisoning and recurrence of pesticide poisoning,cumulative amount of atropine,and hospitalization days were significantly less in patients treated with improvement regimen than those with traditional method ( P <0 05 or P <0 001).Conclusions:The results indicate that the improved regimen is practical and effective in the treatment of acute organophosphorus pesticide poisoning.
出处
《中国危重病急救医学》
CAS
CSCD
1999年第5期294-296,共3页
Chinese Critical Care Medicine
关键词
有机磷农药中毒
治疗
阿托品
解磷定
acute organophosphorus pesticide poisoning improved regimen traditional method atropine Jielin Injection pyraloxime methylchloride cholinesterase
