摘要
用CS及Basc果蝇品系对美尔伊避孕注射液及其配伍的两种成份——醋酸甲地孕酮和雌二醇的毒性及遗传效应进行检测。Basc品系用于检测发生在X染色体上的隐性致死突变。实验结果表明,美尔伊避孕注射液及其配伍的两种成份均元毒性及有害的遗传效应。美尔伊避孕注射液可推广使用。
The physiological toxicity and genetic effect of Mego-E and its two componentsperts: megestrol acetate and estradiol upon two strains of D. melanogaster Canton-S andBasc were studied. Basc strain has been used especially for measurement of the recessivelethal mutation occurrence in X-chromosomes. The results have shown that Mego-E and its two component parts have neither phy-siological toxicity nor harmful genetic effect. Therefore Mego-E might be a potentialand safe contraceptive.
出处
《生殖与避孕》
CAS
CSCD
北大核心
1990年第3期64-66,共3页
Reproduction and Contraception
关键词
生理毒性
遗传效应
美尔伊
避孕药
Physiological toxicity
Recessive lethal mutations
Genetic effects
