摘要
目的探讨肿瘤坏死因子α（ＴＮＦα）、白细胞介素－６（ＩＬ－６）与慢性肝病的关系。方法采用双抗体夹心ＥＬＩＳＡ法对慢性肝病患者血清ＴＮＦα及ＩＬ－６进行检测。结果慢性活动性肝炎组及肝硬变患者的ＴＮＦα及ＩＬ－６指标均显著高于正常对照组（Ｐ＜００１），而慢性迁延性肝炎组与对照组相比无显著性差异（Ｐ＞００５）。
Objective To find out the relationship between tumor necrosis factor α(TNFα),interleukin 6(IL 6) and chronic liver disease.Methods Enzymelinked immunosorbent assay(ELISA) was performed to determine the serum levels of TNFα and IL 6 in the patients with chronic liver disease.Results It was showed that TNFα and IL 6 in both patients with chronic active hepatitis (CAH) and cirrhosis incrcased significantly as compared with normal subjects( P <0 01),but patients with chronic persistent hepatitis (CPH)and normal controls there was no difference.Conclusion The results indicated that TNFα and IL 6 may play an important role in process of fibrosis and prognosis in chronic liver disease.
出处
《武警医学》
CAS
1999年第3期131-132,共2页
Medical Journal of the Chinese People's Armed Police Force
