摘要
本试验进行了三批鸡的免疫研究。第一批试验检测不同类型新城疫疫苗在不同母源抗体水平（高和低）的鸡体上的免疫效果。结果显示，在高母源抗体时免疫，Ｖ４组和油乳剂灭活苗组抗体水平表现较低，而在低母源抗体时免疫，几种疫苗的抗体水平上升得很快，特别Ｌａｓｏｔａ－克隆３０组最明显，而油乳剂灭活苗组的抗体水平保持得最长。根据此结果而制定了不同的免疫程序，进行了第二、第三批免疫试验，并分别在４５天龄及７０天龄时进行强毒攻击。结果表明，在此两批试验中，无论是抗体水平保持得久，还是攻毒保护性好，都是以应用油乳剂灭活苗与Ｌａｓｏｔａ－克隆３０配合使用的组别抗体水平保持得较好，尤其是在７天龄Ｌａｓｏｔａ－克隆３０１头份／只点眼，１４天龄Ｌａｓｏｔａ－克隆３０２头份／只饮水同时肌肉注射０．２５ｍｌ油乳剂灭活苗的组别效果最为理想。
Experiments were undertaken to determine the effectiveness of various vaccination regimes for chicken Newcastle disease(ND).The effect of 4 ND vaccines was determined in chicks with both high and low maternal antibody levels.Results indicate that lower ND antibody titers were seen in chicks with high levels maternal antibodies when vaccinated with V4 and oil-emulsion vaccines as compared to other vaccine groups.However,high,antibody titers were reached in all vaccine groups when chicks with low maternal antibady levels were vaccinated.Due to these results,we designed several vaccination programs,experimental chickens were challenged with NDV at 45 and 70 days of 1 dose of Lasota-clone-30 eye-drip at 7 days of age,2 doses of Lasota-clone-30 in drinking water and 0.25ml oil emulsion vaccine IM.
出处
《广东畜牧兽医科技》
1999年第1期7-10,共4页
Guangdong Journal of Animal and Veterinary Science
关键词
新城疫
免疫程序
鸡
测定
Newcastle disease Vaccination programs
