摘要
[摘要]目的观察低分子肝素钙治疗不稳定型心绞痛的临床疗效及安全性。方法对传统抗心绞痛药肠溶阿司匹林等治疗不佳的不稳定型心绞痛患者49例加用低分子肝素钙皮下注射，5000u／次，1次／12h，连用7d。结果49例患者加用该药后，与治疗前相比，心绞痛日均发作次数，每次心绞痛平均持续时间、硝酸甘油含片日均用量；24h动态心电图检出的心肌缺血次数、缺血持续时间、缺血最长时间、室性早搏数、阵发性室速次数与治疗前相比两组均减少。治疗前后比较，差异具有显著性（P〈0．01）。结论低分子肝素钙治疗不稳定型心绞痛有效、安全、值得临床推广应用。
Objective To observe clinical treatment and safety of the low molecular weight heparin to unstable angina. Methods Of traditional aspirin and other anti-angina drugs in poor treatment of 49 unstable angina pectoris patients with LMWH subcutaneously, 5000u / times, ql2h, 7 days. Results 49 patients after LMWH treatment, the number of angina attacks daily, The average duration of each angina pectoris, nitroglycerin tablet daily dosage; 24h Holter detected myocardial ischemia times, the duration of ischemia and ischemia maximum time, the number of premature ventricular contractions, the number of paroxysmal ventricular tachycardia Compared with the two groups before treatment were reduced, the difference was significant （P〈0.01） . Conclusion The treatment with LMWH of unstable angina pectoris is effective, safe and worthy of clinical application.
关键词
心绞痛
不稳定型
低分子肝素
钙药物疗法
Angina pectoris
Unstable
Low molecular weight heparin
Drug therapy
