摘要
目的利用海德堡视网膜断层扫描仪(Heidelberg retina tomography,HRT)检查对LASIK术后视盘的形态学、视网膜神经纤维层(retinal nerve fiber layer thickness,RNFL)进行定量分析,评价LASIK对其可能产生的影响。方法拟行LASIK的患者56例(56眼),分别于术前、术后1d、7d、30d行HRT检查,获取视盘的盘沿面积(rimarea,RA)、视杯/视盘面积(cup/disc area ratio,C/D)、视杯容积(cup volume,CV)、盘缘容积(rim volume,RV)、视盘轮廓高度线 (height variation contour,HVC)、平均RNFL厚度。结果 LASIK对视盘形态各参数有不同的影响:RA:术前、术后1d、7d、30d分别为(1.45±0.32)mm2、(1.41±0.32)mm2、(1.42±0.31)mm2、(1.43±0.30)mm2,术后1d较术前明显减小(P<0.05),术后7d、30d与术前比较差异均无统计学意义(均为P>0.05);HVC:术前、术后1d、7d、30d分别为(0.53±0.14)mm、(0.47±0.10)mm、(0.47±0.13)mm、(0.47±0.14)mm,术后各时间点与术前比较,差异均有统计学意义(均为P<0.05);RV:术前、术后1d、7d、30d分别为(0.54±0.20)mm3、(0.48±0.17)mm3、(0.47±0.18)mm3、(0.48±0.17)mm3,术后各时间点与术前比较,差异均有统计学意义(均为P<0.05);RNFL厚度:术前、术后1d、7d、30d分别为(0.36±0.09)mm、(0.33±0.08)mm、(0.31±0.10)mm、(0.32±0.10)mm,术后各时间点与术前比较,差异均有统计学意义(均为P<0.05);而C/D值参数在手术前后无明显变化,术前、术后1d、7d、30d分别为0.18±0.12、0.19±0.12、0.20±0.12、0.19±0.12,差异均无统计学意义(均为P>0.05)。结论 LASIK术后早期视盘HVC、RNFL厚度、RV、RA各参数较术前均有不同程度下降,而C/D值变化不大。
Objective To quantitative analyze the optic disc morphology and retinal nerve fiber layer（RNFL） thickness by Heidelberg retina tomography（HRT）,and evaluate the possible influence of LASIK on optic disc morphology.Methods The rim area（RA）,cup/disc area ratio（C/D）,cup volume（CV）,rim volume（RV）,height variation contour（HVC） and mean RNFL thickness were examined in 56 myopic patients（56 eyes） who planed to receive the LASIK by HRT before operation and at postoperative 1 day,7 days and 30 days.Results Before operation and at postoperative 1 day,7 days and 30 days,RA were（1.45±0.32）mm2,（1.41±0.32）mm2,（1.42±0.31）mm2,（1.43±0.30）mm2,there was statistical difference only between before operation and at postoperative 1 day（P〈0.05）;HVC was（0.53±0.14）mm,（0.47±0.10）mm,（0.47±0.13）mm,（0.47±0.14）mm,there were statistical differences between before and after operation（All P〈0.05）;RV were（0.54±0.20）mm3,（0.48±0.17）mm3,（0.47±0.18）mm3,（0.48±0.17）mm3,there were statistical differences between before and after operation（All P〈0.05）;RNFL thickness were（0.36±0.09）mm,（0.33±0.08）mm,（0.31±0.10）mm,（0.32±0.10）mm,there were statistical differences between before and after operation（All P〈0.05）;C/D were 0.18±0.12,0.19±0.12,0.20±0.12,0.19±0.12,there was no statistical difference between before and after operation（All P〈0.05）.Conclusion LASIK has different influence on each parameter of optic disc morphology at the early stage after surgery,the HVC,RNFL thickness,RV and RA are lower than before operation,but C/D is stable.
出处
《眼科新进展》
CAS
北大核心
2010年第9期863-865,共3页
Recent Advances in Ophthalmology
