摘要
目的观察谷胱甘肽治疗酒精性肝病的临床疗效。方法将酒精性肝病患者60例随机均分为治疗组和对照组,治疗组用谷胱甘肽治疗,对照组用门冬氨酸钾镁治疗,疗程均为1个月。结果治疗组总有效率为96.67%,对照组为66.67%,两组比较差异有显著性(P<0.01);治疗组平均显效时间为(10.7±6.4)d,明显少于对照组的(21.4±7.7)d(P<0.01);治疗组丙氨酸氨基转移酶、天门冬酸氨基转移酶、谷氨酰转肽酶复常率分别为93.33%,93.33%,90.00%,对照组分别为46.67%,40.00%,40.00%,两组比较差异有显著性(P<0.01)。结论谷胱甘肽治疗酒精性肝病疗效确切、安全。
Objective To observe the clinical efficacy of glutathione （GSH） on the treatment of alcoholic liver diseases.Methods Sixty patients with alcoholic liver diseases were randomly divided into two groups,30 cases in each group.The treatment group was treated with GSH and the control group with potassium magnesium aspartate for 30 d.Results The total effective rate was 96.67%in the treatment group and 66.67%in the control group with significant difference（P〈0.01）.In treatment group,the mean effective time was （10.7±6.4） d and the normalization rates of ALT,AST and RGT were 93.33%,93.33%and 90.00%respectively,those in the control group were （21.4±7.7） d,46.67%,40.00%and 40.00%respectively with significant difference（P〈0.01）.Conclusion GSH is an effective agent for the treatment of alcoholic liver diseases,which is more effective than potassium magnesium aspartate.
出处
《中国药业》
CAS
2010年第17期63-63,共1页
China Pharmaceuticals
关键词
谷胱甘肽
酒精性肝病
疗效
门冬氨酸钾镁
GSH
alcoholic liver diseases
curative effect
potassium magnesium aspartate
