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靶控输注丙泊酚复合瑞芬太尼诱导对开颅手术患者血流动力学的影响 被引量:5

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摘要 目的进一步提高开颅手术麻醉诱导的安全性。方法将50例ASAⅠ~Ⅲ级择期全麻颅脑手术患者随机分成观察组和对照组各25例,分别予瑞芬太尼和丙泊酚靶控输注及静脉推注,麻醉诱导气管插管。观察两组肌僵硬现象,意识消失时间,插管前及插管后1min动脉压、心率。结果两组均未发现肌僵硬现象,导时的动脉压及HR均明显低于基础值(P均<0.05);观察组意识消失时间明显短于对照组(P<0.05);观察组气管插管后MBP升高不明显,心率几乎未见升高,对照组MBP升高明显。结论靶控输注丙泊酚复合瑞芬太尼用于开颅手术麻醉诱导,能较好的消除气管插管反应,不良反应少。
作者 王云川
机构地区 琼海市人民医院
出处 《山东医药》 CAS 北大核心 2010年第31期50-51,共2页 Shandong Medical Journal
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