摘要
本文通过对168名妇女的空腹尿钙/肌酐、尿羟脯氨酸/肌酐及141名妇女的血碱性磷酸酶测定结果的分析,评价了绝经前后妇女骨代谢变化的状况。结果表明:妇女绝经后较绝经前、50岁后较50岁前其骨吸收和骨形成都显著增快;骨吸收速度上升后无下降趋势,骨形成速度的上升持续约20年后略有下降;骨吸收和骨形成速度的增快呈相关性。
In this study, we determined fasting urine the caloium/oreatinine ratios, tirine hydroxyproline/oreatinine ratios in 168 subjects; blood AKP activity in 141 subjects, to observe the state of bone turnover (bone resorption and bone formation). Eesults showed that bone turnover in women after menopause or ≥50 yeais Old is significantly higher than that in women before menopause or<50 years old. Bone resorption has no tendency of decreasing once it has risen to a high level. Bone formation begins to decrease 20 years after menopausa. There is significant correlation between bone resorption and bone formation.
出处
《上海医科大学学报》
CSCD
1990年第5期374-377,共4页
Journal of Fudan University(Medical Science)
关键词
骨代谢
绝经
碱性磷酸酶
bone turnover
menopause
alkaline phosphatase
