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酶法测定血清总胆汁酸在肝病诊断中的应用 被引量:2

Application of Enzymatic Method for the Measurement of Total Bile Acids in Serum for the Diagnosis of Liver Diseases
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摘要 通过对英国RANDOX公司生产的酶法测定总胆汁酸试剂盒临床应用应用的可行性进行评价和测定肝病患者血清TBA含量,评价酶法测定血清TBA在各种肝病诊断中的应用价值。结果;批内cv为1.27%和0.8%,批间cv2.09%和1.50%,回收率为101.2%,线性范围0-300μmol/L。 The enzymatic method for the measurement of total bile acids inserum was applicated to evaluate the clinical reliability and diagnosticvalue in liver diseases. The results showed that the total bile acidsconcentration leval in the acute icteric hepatitis group, acute anicterichepatitis group, chronic active hepatitis group, chronic persistent hep-atitis group, and cirrhosis of liver group were 184. 1± 136.8μmol/L (P < 0.001), 67.3 ± 47.9μmol/L (P < 0.001) ; 35.6 ± 14.35μmol/L (P< 0.001),9.5 ± 8.72 μmol/L (P >0.05) and 88.3 ±52.3μmol/L (P < 0. 001 ), respectively. The positive rate were100%, 90%,90%,0 and 100%, respectively. It suggessted that theenzymatic method for the measurement of total bile acids in serum isprecise and accurate. It will help to diagnose defferent types of hepaticdiseases by measuring total bile acids in serum.
出处 《贵州医药》 CAS 1999年第2期82-84,共3页 Guizhou Medical Journal
关键词 胆汁酸 肝硬化 肝炎 诊断 测定 Total bile acids, Hepatitis, Cirrhosis of liver
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参考文献2

  • 1刘树业 宋继昌 等.肝病患者血清与胆汁中七种结合胆酸的高效液相色谱分析[J].中华医学检验杂志,1993,16:152-154.
  • 2魏有仁 孙先高 等.血清胆汁酸的酶法测定及其评价[J].中华医学检验杂志,1993,16:11-14.

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  • 1程峰涛 李铎 等.乙型肝炎后肝硬化患者血清总胆汁酸测定的意义[J].中华消化杂志,1998,18(2):92-92.
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