摘要
目的:探讨药物灌注治疗非肿瘤性乳管系统疾病的可行性,寻找其治疗新途径。材料与方法:经改进乳腺导管造影方法获取清晰准确的导管造影检查结果,再经溢液病理涂片、泌乳术测定排除肿瘤性病变并无禁忌症的导管扩张症78例,单纯导管炎症29例,囊性增生5例。经临床保守治疗疗效不显著后,即选择对溢液乳孔注入药物治疗,隔日1次,4次为一疗程。结果:经一疗程治疗后46(41.1%)例溢液停止,疼痛消失;36(32.1%)例溢液明显减少,溢液色泽变清,疼痛缓解;经2～4疗程治疗后,20例(19.6%)溢液逐渐变少直至消失,疼痛明显减轻或消失;10例(7.2%)因溢液时间长,病情迁延反复,经4个疗程治疗后仍有溢液。结论:经选择性乳腺导管造影,能够清晰观察到导管内细微病灶,明确诊断的非肿瘤性乳头溢液,经溢液乳孔注入药物治疗,效果显著(总有效率达92.8%),具有临床推广应用价值。
Purpose：To explore the feasibility of drug perfusion treatment of non-neoplastic diseases in breast duct system and to research new ways of treatment.Materials and Methods：All selective cases includeing duct dilatation in 78 cases,symple duct inflammation in 29 cases,cystic hyperplasia in 5 cases were not significant effect by clinical conservative treatment and no contraindications,each case was injected drugs through nipple discharge hole one time day interval,fore times were a course,each cases was performed galactography of improvement methods and obtained clear accurate inspective results,the nipple discharge was examined by pathological smear to exclude neoplastic lesions.Results：The discharge were stoped and pain were disappeared after one course treatment in 46 cases（41.1%）,the discharge were decreased significantly,the color of liquid were changed clear and pain were relieved in 36 cases（32.19%）,the discharge were gradually decreased until disappeared after 2-4 course in 29 cases（19.6%）.Conclusion：The treatment effect？are significant with injecting drugs to nipple discharge hole in non-neoplastic lesions（total effect ratio 92.8%）,it has high clinical applicational value.
出处
《现代医用影像学》
2010年第2期79-81,共3页
Modern Medical Imageology
