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早期新鲜羊膜移植治疗难治性角膜溃疡疗效观察 被引量:4

Clinical effect of early fresh amniotic membrane transplantation in refractory corneal ulcer
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摘要 目的:探讨羊膜移植术在难治性角膜溃疡中的临床治疗效果。方法:患者角膜病灶清创后,将制备好的新鲜羊膜移植,共治疗难治性角膜溃疡25例(25眼),术后随访3~36个月。结果:25例角膜溃疡患者术后均未见排斥反应,角膜感染得到有效控制,3~4周角膜溃疡上皮愈合,角膜溃疡区留下不同程度的瘢痕,角膜溃疡患者视力均有不同程度的提高,无一例角膜溃疡复发,未出现角膜穿孔病例。结论:新鲜羊膜移植治疗难治性角膜溃疡是一种有效的治疗方法。 Objective:To evaluate the therapeutic effect of amniotic membrane transplantation(AMT) in refractory corneal ulcer.Methods: After debriding of patients' cornea focus,explant the well prepared fresh amniotic.Fresh amniotic was performed in 25 patients(25 eyes) of refractory corneal ulcer,we followed up for 3~36 months after operation.Results:No actual rejection was observed in all 25 corneal ulcer patients,the infection were effectively controlled after surgery.Corneal ulcer epithelium healed overall in 3 to 4 weeks,varying degrees of scar was left on corneal ulcer area.Corneal ulcer patients' vision were all improved in various degree,recur of corneal ulcer was out of observe,corneal perforation was unobserved either.Conclusion:Fresh AMT is a very effective method for treatment to refractory corneal ulcer.
作者 高明华
出处 《中国当代医药》 2010年第22期248-249,共2页 China Modern Medicine
关键词 角膜溃疡 羊膜移植 角膜炎 视力 Corneal ulcer Amniotic membrane transplantation Keratitis Visual
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