摘要
目的:探讨伴有非胰岛素依赖型糖尿病(NIDDM)冠心病患者的冠状动脉病变及其临床特征.方法:用冠脉造影方法分析了850例伴有NIDDM(153例)和不伴有NIDDM(697例)冠心病冠脉病变特点并将临床特点加以对照研究.结果:冠心病合并NIDDM患者伴高血压、脑卒中、高脂血症及阳性家族史率较不伴有NIDDM冠心病患者明显升高,该组患者无痛型较多,病情重,住院期间病死百分比高,该组患者易出现中重度冠状动脉病变及三支病变(P<0.01),左室射血分数(EF)下降.结论:糖尿病是冠状动脉病变和心功能不全的独立危险因素,糖尿病的早期诊断对冠心病预后非常重要.
AIM: To study the coronary artery lesions and clinical features in patients with coronary heart disease(CHD) coexisting with noninsulin dependent diabetes mellitus(NIDDM). METHODS: 850 cases of CHD patients were divided into 2 groups: patients with NIDDM, and patients without NIDDM. The coronary lesions were compared between the 2 groups by coronary artery angiography(CAG) and the clinical characteristics were also studied between the 2 groups. RESULTS: More patients with NIDDM had hypertension, stroke, hyperlipemia and family history of NIDDM or CHD. More patients with NIDDM had painless chest pain, and the mortality rate in NIDDM group was higher than that of control group. More patients with NIDDM suffered from middle to severe stenosis of coronary artery and triple CHD and low ejection fraction than without(P<0.01). CONCLUSION: NIDDM is an independent risk factor for CHD and heart function and the early diagnosis of NIDDM is very important for the prognosis of CHD.
出处
《第四军医大学学报》
1999年第4期304-306,共3页
Journal of the Fourth Military Medical University