摘要
临床输血是肿瘤治疗的重要支持手段之一。输血对肿瘤患者起着双重作用,一方面可纠正患者的贫血状况,提高血氧含量,加速肿瘤细胞氧化和变性坏死;另一方面也可能引起受者免疫抑制,导致肿瘤复发和术后感染。滤除白细胞输血能减少输血不良反应,合理进行肿瘤患者围手术期的自体输血是国内外医学界关注的问题。本文就输血对肿瘤患者治疗的支持作用、输血和免疫抑制、输血与肿瘤患者术后感染和肿瘤复发、去白细胞输血及肿瘤患者自体血输注等问题进行了综述。
Clinical blood transfusion is one of the most important supportive therapy for patients with tumor. The blood transfusion has dual effects for patients with tumor. First, blood transfusion can rectify anemia and improve oxygen saturation, accelerate oxidation and necrosis for tumor cells; the second, blood transfusion can induce immunosuppression, tumor recurrence and postoperative infection for tumor patients. Filtering white blood cells （WBC） before blood transfusion can decrease the incidence of the adverse reactions. The rational perioperative autotransfusion for patients with tumors is focus to which the world medical sciences pay close attention. In this article, the support effect of blood transfusion for treatment of tumor patients, blood transfusion and immunosuppresion, blood transfusion and post- operative infection and relapse of tumor patients, depleted leukocyte blood transfusion and autologous transfusion of tumor patients are reviewed.
出处
《中国实验血液学杂志》
CAS
CSCD
2010年第4期1092-1095,共4页
Journal of Experimental Hematology
关键词
输血
肿瘤治疗
免疫抑制
感染
肿瘤复发
blood transfusion
tumor therapy
immunosuppression
infection
tumor recurrence
