摘要
目的比较卡维地洛治疗维吾尔族与汉族扩张型心肌病心力衰竭的临床疗效。方法扩张型心肌病患者41例,其中维吾尔族22例,汉族19例,维吾尔族组心功能Ⅱ级9例,Ⅲ级10例,Ⅳ级3例;汉族组心功能Ⅱ级6例,Ⅲ级7例,Ⅳ级6例。均于慢性心功能不全基础治疗上加用卡维地洛。治疗6个月观察其疗效。结果维吾尔族组有效率95.46%,汉族组有效率94.74%。左室射血分数(LVEF)的改善汉族组略优于维吾尔族组,而左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)的改善两组无明显差异(P<0.01)。结论卡维地洛可显著改善心功能,明显提高扩张型心肌病患者生活质量,在新疆维吾尔族与汉族扩张型心肌病患者中应用无明显疗效差异。
Objective To compare the therapeutic effect of carvedilol on dilated cardiomyopathy（DCM） between Uygur and Han patients in Turufan.Methods Among 41 patients,22 of Uygur,19 of Han;In Uygur group,9 of the heart function（NYHA）Ⅱclass,10 of Ⅲ class,3 of Ⅳ class,In Han group,6 of the heart function（NYHA）Ⅱclass,7 of Ⅲ class,6 of Ⅳ class.All were given Carvedilol based on the standard therapy according to the guidline.The clinical effect was compared after six months of treatment.Results The effective power was 95.46% and 94.74% respectively in Uygur and Han group.the improvement of LVEF was a little better in Han group than in Uygur group;And the improvement of LVEDD、LVESD were no significantly differences between two groups.Conclusion Carvedilol can increase cardiac function obviously,improve the life quilty of patients with DCM,and there is no significantly differences in clinical benefits between Uygur and Han patients with DCM when accept a standard therapy highlighted Carvedilol.
出处
《实用心脑肺血管病杂志》
2010年第9期1231-1233,共3页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
