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卡维地洛治疗扩张型心肌病充血性心力衰竭的疗效评价 被引量:3

Clinical effects of Carvedilol on dilated cardiomyopathycongestive heart failure
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摘要 目的:评价第三代β受体阻滞剂卡维地洛治疗扩张型心肌病(DCM)充血性心力衰竭的临床疗效。方法:80例DCM充血性心力衰竭患者,随机分为接受常规治疗(营养心肌、洋地黄、利尿剂、血管紧张素转换酶抑制剂)组和常规治疗加卡维地洛组,检测治疗前后心率、血压和左心室功能及结构的变化。结果:治疗前两组间各项指标比较差异无显著性(P>0.05);治疗3个月后,常规治疗组治疗前后心率比较差异无显著性,其他各项指标差异均有显著性(P<0.05);卡维地洛组各项指标治疗前后比较差异均有显著性(P<0.05);治疗后卡维地洛组心率、血压和左心室功能及结构改善效果优于常规治疗组(P<0.05)。结论:卡维地洛能够明显改善DCM充血性心力衰竭患者心脏收缩和舒张功能,逆转左室重构,对DCM充血性心力衰竭疗效显著。
出处 《吉林大学学报(医学版)》 CAS CSCD 北大核心 2005年第4期618-619,633,共3页 Journal of Jilin University:Medicine Edition
基金 吉林省科技厅资助课题(2003042002)
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