摘要
【目的】通过与丙泊酚比较评价依托咪酯乳剂复合麻醉在无痛人流术中的应用价值【方法】将80例ASAⅠ～Ⅱ级自愿终止妊娠者随机分为依托咪酯组（Ⅰ组）和丙泊酚组（Ⅱ组），每组40例。两组孕妇先静脉注射芬太尼1gg／kg；Ⅰ组孕妇随后静脉注射咪唑安定0．03mg／kg和依托咪酯0．3nag／kg，入睡后开始手术，如有体动等麻醉偏浅反应时静脉追加依托咪酯0．1～O．2mg／kg；Ⅱ组孕妇静脉注射丙泊酚2mg／kg，入睡后开始手术，如有体动等麻醉偏浅反应时静脉追加丙泊酚0．5～1mg／kg；记录两组孕妇麻醉前、手术前、手术中的平均动脉压（MAP）、心率（HR）、呼吸频率（RR）脉搏血氧饱和度（SpO2）、手术时间、意识消失时间、苏醒时间、行走恢复时间及不良反应的发生情况。【结果】麻醉过程中试验组孕妇循环更稳定；苏醒质量与对照组没有明显差别。【结论】依托咪酯伍用小剂量的咪唑安定和芬太尼用于人工流产术不失为一种合适的麻醉。
[Objective]To compare the value of etomidate emulsion combined anesthesia vs propofol in tJainless induced abortion. [Methods] Eighty ASA Ⅰ～Ⅱ pregnant women who underwent artificial abortion were randomized to etomidate group （group Ⅰ, n =40） and propofol group （group Ⅱ, n =40）. All pregnant women were infused fentanyl 1μg/kg firstly. The group Ⅰ were anesthetized with midazolam 0.03mg/kg and etomidate 0.3mg/kg, and additionally infused etomidate 0.1-0.2mg/kg if necessary. The group Ⅱ were anesthetized with propofol 2 mg/kg, and were additionally infused propofol 0. 5 -1 mg/kg if necessary. The mean arterial pressure（MAP）, heart rate（HR）, respiratory rate（RR） and SpO2 were monitored. In addition, the time of operation, unconsciousness, recovery, wal.king recovery and complications were recorded. [Resuits] The hemodynamics of the pregnant women in group Ⅰ was more smoothly than that in group 11. There was no obvious difference in recovery quality between the two groups. [Conclusion]Etomidate emulsion anesthesia combined with midazolam and fentanyl is suitable for painless induced abortion.
出处
《医学临床研究》
CAS
2010年第7期1256-1258,共3页
Journal of Clinical Research
