摘要
目的:观察急诊ICU危重患者强化胰岛素治疗的临床疗效及对其预后与死亡率的影响。方法:将68例急诊ICU血糖水平>11.1mmol/L的危重患者随机分成治疗组及对照组,治疗组给予强化胰岛素治疗,将血糖控制在4.4~6.1mmol/L;对照组给予常规胰岛素治疗,将血糖控制在8.6~11.1mmol/L。结果:治疗组中使用抗生素天数、静脉用胰岛素天数、入住ICU天数、使用机械通气天数、院内感染发生率均低于对照组,死亡率无显著性差异,低血糖发生率明显高于对照组。结论:急诊ICU危重患者强化胰岛素治疗可以改善危重患者的病情,降低院内感染率,缩短患者住院天数,减轻患者经济负担;但需高度警惕低血糖的发生。
Objective:To observe the efficacy of intensive insulin therapy in Emergency intensive care unit (ICU) critically ill patients,and assess the impact on the prognosis and mortality.Methods:68 eases of critically ill ICU patients with acute glucose levels above 11.1mmol/L were randomly assigned to treatment group (34 patients)and control group (34 patients),treatment group received intensive insulin therapy,which blood glucose was maintained within a relatively low and narrow range (4.4 to 6.1 mmol/L),control group was given conventional insulin therapy, glucose control with a target of 8.6-11. 1mmol/L.Results:The following of the treatment group,including the number of days of using antibiotics and intravenous insulin,the length of ICU stay, the number of days of mechanical ventilation were shorter and the infection rate was lower than the control group,while the incidence of hypoglycemia was significantly higher;the mortality rate was no significant difference between the two groups.Conclusion:Intensive insulin therapy admitted to improve the condition of Emergency ICU critically ill patients,to reduce nosoeomial infection and shorten hospitalization days,to alleviate the financial burden of patients;but be highly vigilant against the occurrence of hypoglycemia.
出处
《中国医药导刊》
2010年第7期1123-1124,共2页
Chinese Journal of Medicinal Guide
关键词
强化胰岛素治疗
急诊ICU
病情及预后
低血糖
Intensive insulin therapy
Emergency ICU
Condition and prognosis
Hypoglycemia