摘要
目的:观察中西医结合疗法对急性脑梗塞患者治疗前后血清可溶性血管细胞粘附分子(sVCAM-1)的变化水平。方法:中西药组采用西医常规疗法加破瘀通络汤治疗,西药组采用西医常规疗法,采用酶联免疫法检测治疗前后患者血清可溶性血管细胞粘附分子(sVCAM-1)水平。结果:中西药组及西药组治疗前sVCAM-1水平与正常对照组比较明显增高(P<005);治疗后两组sVCAM-1水平均有明显下降(P<005);而中西药组降低较西药组明显(P<005),与正常对照组比较,无显著性差异(P>005)。结论:提示中西医结合疗法治疗本病的作用机理与调节机体的免疫状态有关。
Objective: To investigate the change of serum soluble vascular cell adhesion molecule 1 (sVCAM-1) in acute cerebral infarction patients treated with integrated traditional Chinese and western medicine (TCM WM). Methods: Serum sVCAM-1 level of patients treated with TCM WM or western medicine alone was measured by ELISA, and compared with that of healthy person. Results: TCM WM could reduce the sVCAM-1 level in patients with cerebral infarction (P<0 05). The therapeutic effect of TCM WM was better than that of western treatment alone, P<0 05. Conclusion: The therapeutic mechanism of TCM WM may be related with the modulation on immune status of patients.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1999年第1期27-28,共2页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
脑梗塞
中西医结合治疗
免疫功能
SVCAM-1
cerebral infarction, integrated traditional Chinese and western medicine, immune function, soluble vascular cell adhesion molecule 1