摘要
为探讨小梁切除术中应用丝裂霉素C(MMC)致前房出血的原因。方法:回顾性分析99例142眼原发性青光眼小梁切除术后前房出血的情况,对术中未应用MMC与术中巩膜瓣上及巩膜瓣下放置0.3~0.4mg/mlMMC4~5分钟,术后前房出血的发生率进行了比较。结果:未应用MMC组前房出血的发生率为4.17%,巩膜瓣上置MMC组前房出血的发生率为6.06%,巩膜瓣下置MMC组前房出血的发生率为37.84%,明显高于前两组,P<0.01。结论:巩膜瓣下置MMC组前房出血的发生率明显增高,可能是MMC对睫状体血管内皮细胞损伤的结果。
Objective:To study the cause of hyphema after trabeculectomy with mitomycin C(MMC).Methods:Obsered the hyphema after trabeculectomy in 99 cases(142 eyes)of primary glaucoma and compared the propotion of hyphema with three groups:not applied MMC,applied to episclera and applied to scleral bed after scleral flap with 0 3~0 4mg/ml MMC during trabeculectomy for 4~5 minutes.Results:The proportion of hyphema in the group not applied MMC,applied to scleral and to scleral bed after scleral flap was 4 17%,6 06% and 37 84% separately.The proportion of hyphema in the group applied MMC to scleral bed was significantly higher than that of the other groups (P<0 01).Conclusion:Higher proportion of hyphema in the group applied MMC to scleral bed,possibly,is caused by injury of ciliary vascular endothelium.
出处
《中国实用眼科杂志》
CSCD
1999年第3期166-167,共2页
Chinese Journal of Practical Ophthalmology