摘要
目的为探讨放射性龋发病的相关因素和防治措施。方法本文共收集22例头颈部放疗患者，对其中的10例分别于放疗前和放疗后二个月进行唾液流达和离休菌斑产酸性的检测，并比较了放疗患者与正常人唾液缓冲能力的差别。结果头颈部放疗后唾液流速明显下降。放疗后二个月刺激唾液流速可由放疗前的1．17ml／min下降到0．34ml／min，头颈部放疗患者的唾液缓冲能力显著低于正常人（P＜0．01）。离体菌斑的产酸性放疗后显著大于放疗前（P＜0.01）。结论放疗后唾液流过明显下降，离体菌斑的产酸性明显增加。
Objective To study the etiologic factors of radiation caries. Methods 22 patients with malignantlesions in the head and neck were included in this study. The stimulated salivary flow rate and plaque pH response in vitrowere carried out in 10 of them immediately before radiotherapy and at 2 months after its termination. The salivarybuffering capacity and flow rate of patients who had received head and neck radiotherapy were compared with those of 14healthy controls. Results The mean flow rate of the stimulated salivary secretion decreased from a preirradiation 1. 17ml/ min to 0. 34 ml/min at two months after irradiation (P< 0. 01 ). The buffering capacity of saliva in patients who hadreceived head and neck radiotherapy was lower than that of healthy people (P< 0. 01 ). The dental plaques produced moreacid in vitro after radiotherapy than before irradiation (P< 0. 01 ). Conclusion The changes in oral environment followingradiotherapy may cause radiation caries to happen.
出处
《现代口腔医学杂志》
CAS
CSCD
1999年第1期36-38,共3页
Journal of Modern Stomatology
