摘要
目的:评价丹鹿通督片治疗瘀阻督脉型腰椎管狭窄症的临床疗效、安全性。方法:采用双盲随机对照方法,丹鹿通督片试验组401例,骨仙片对照组201例。结果:①试验组临床总有效率93.5%,显效率56.9%,对照组总有效率76.1%,显效率28.4%,两组比较差异有统计学意义,试验组疗效明显优于对照组。②两组在改善中医证候方面均有效,但试验组疗效明显优于对照组。③两组治疗患者症状疗效均显著,试验组在改善患者间歇性跛行、腰部疼痛、腰椎过伸试验、跟腱反射、皮肤感觉减退疗效方面明显优于对照组。④试验组治疗患者跛行、腰痛症状起效比对照组快。⑤丹鹿通督片在治疗过程中未见明显不良反应。结论:丹鹿通督片治疗瘀阻督脉型腰椎管狭窄症效果确切,起效快,是一种安全有效的口服药物。
Objective：To evaluate the clinic efficacy and safety of Danlu Tongdu Tablet （DTT） for the treatment of lumbar spinal stenosis belonging to stasis in DU Meridian. Methods：The results in 401 cases of DTT group and201 cases of Guxianpian （GXP） control group were observed by using randomized double-blind controlled trials. Result：① The gross efficacy and the significant efficacy of DTT group was 93.5% and 56.9%, contrastively, that of GXP group was 76.1% and 28.4% respectively. There was significant difference between the 2 groups, with efficacy of DTT group superior to that of GXP group. ② Traditional Chinese medicine syndromes in both groups were improved, and DTT group presented better improvement than GXP group. ③ The patients＇ symptoms in both two groups were improved. Especially, in contrast to GXP group, DTT group showed more efficacies in intermittent claudication, lumbago, lumbar extension test, Achilles tendon reflex and the decline of cutaneous sensory. ④ The demonstratration of improvement of intermittent claudication and lumbago in DTT group was earlier than GXP group. ⑤ In the course of treatment, there was no evident adverse.Conclusion：DTT is an effective, quick and safe medicine to treat lumbar spinal stenosis belonging to stasis in DU Meridian.
出处
《中国中医骨伤科杂志》
CAS
2010年第7期13-16,共4页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
关键词
丹鹿通督片
腰椎管狭窄症
中药治疗
Danlu Tongdu Tablet
Lumbar spinal stenosis
Traditional Chinese medicine therapy
