摘要
目的明确硒拮抗砷致小鼠微核变化的可行性及剂量特征。方法小鼠骨髓微核试验。结果与对照组相比，染硒同时染砷，硒可明显地拮抗砷诱发小鼠微核变化的作用，且呈剂量－反应关系。结论硒对砷致小鼠微核变化具有拮抗作用；
Objective To clearify the fesibility of antagonism of selenium against arsenic induced micronuclei in mice and its dose characteristics.Methods Bone Marrow Micronuclei (BMM) assay in mice was used.Results In comparesion with control group,coexposure of selenium and arsenic to mice could induce a dose effect antagonism of selenium against arsenic induced micronuclei in mice.Conclusions Selenium can antagonize the arsenic induced micronuclei in mice and this gurrantee a scientific evidence for both further study and field intervention of selenium against arsenic toxity
出处
《中国地方病学杂志》
CAS
CSCD
1999年第1期5-6,共2页
Chinese Jouranl of Endemiology
基金
山西省教委青年学科带头人培养基金
关键词
硒
骨髓微核
拮抗作用
砷中毒
小鼠
Arsenic Selenium Bone marrow micronucleus Antagonism
