摘要
目的探讨吸入一氧化氮（NO）治疗不同类型的肺动脉高压的适应证及疗效。方法采用BG－951型一氧化氮治疗仪治疗先天性心脏病（CHD）伴肺动脉高压（PH）惠儿81例、高原性肺水肿22例、新生地持续肺动脉高压（PPHN）10例、肺心病20例、哮喘10例，共计5种类型143例患者。结果对CHD伴PH患儿可显著降低PAP（P＜0．01），对高原肺水肿患者肺部湿性罗音和X线胸片阴影消失时间比常规治疗显著缩短（P＜0．01），对PPHN患儿氧合指数显著改善，肺动脉压力降低（P＜0．05），对肺心病血氧分压及血氧饱和度明显改变（P＜0．05），对10例哮喘患者肺通气功能改变率为20％有4例，改变率为10％有3例。结论BG－951型一氧化氮治疗仪性能稳定可靠，治疗多种肺动脉高压安全、有效。
Objective To study the indication and effectiveness of NO inhalation in acute all types of pulmonary hypertension. Methods Using BG - 951 NO inhaled instrument to cure 81 children wtih congerital heart desease (CHD) and pulmonary hyperension(PH) ,22 high - altitude pulmonary edema. 10 Newborns with persistent pulmonary hypertension (PPHN), 20 patients with pulmonary disease, 8 patients with bronchial tone, there are five types and 141 patients in all. Results For CHD and PH children, PAP can be reduced (P<0.01); For high- altitude pulmonary edema patients, the lung noist rales and the confluent of chest filme disapper quickly more than usual treatment (P < O.01); o0r PPHN, oxygenationand pulmonary artery pressure obviously improved (p< 0.05); For pulmonary disease patients, blood oxide pressure and blood oxide saturation can be markedly increased (P < O.05);For bronchial tone patients, the lung function of the lO cases,4 Patients show almost 20% improvement, 3 patients show 10% improvement. Conclusion BG - 951 instrument of inhaledntric oxide is very effective on these diseases.
出处
《广东医学》
CAS
CSCD
1999年第1期8-10,共3页
Guangdong Medical Journal
基金
广东省重点科研项目!9622044-02
