摘要
目的探讨原发性肝癌的治疗方法和预后因素。方法通过随访回顾性分析121例经股动脉穿刺行经肝动脉化疗栓塞术(Transcatheter arterial chemoembolization,TACE)治疗原发性肝癌患者的病例资料,依据影像学及生存时间判断疗效,并对影响预后的因素进行分析。结果 1年、2年、3年生存率分别为47.1%、11.6%、4.1%,中位生存期15.2个月。完全缓解(CR)2例,部分缓解(PR)33例,总有效率(CR+PR)28.9%。对患者生存期影响显著的因素包括临床分期、术前肝功能、肿瘤大体形态和TACE次数。结论影响原发性肝癌预后的影响因素有多种,TACE是治疗原发性肝癌的有效治疗手段,可提高生活质量,延长患者生存期。
Objective To study the therapeutic means and analyze the prognostic factors for primary hepatocellular carcinoma.Methods 121 cases with primary hepatocellular carcinoma who received transcatheter arterial chemoembolization（TACE）were followed up retrospectively and the prognostic factors were analyzed according to imagiology and the survival time.Results For these patients who received TACE,the survival rates of 1,2 and 3 years were 47.1%,11.6% and 4.1% respectively,and the median survival time was 15.2 months.The overall response rate was 28.9% including 2 complete remission（CR）and 33 partial remission（PR）.The related factors which significantly affected the survival rate contained clinical staging,liver function before operation,tumor configuration and number of TACE.Conclusion There were many factors that affected the prognosis of primary hepatocellular carcinoma.TACE was an effective therapeutic means,and this treatment can improve life quality and prolong survival time.
出处
《中华全科医学》
2010年第7期841-842,共2页
Chinese Journal of General Practice
关键词
原发性肝癌
栓塞
预后因素
Hepatocellular carcinoma
Embolization
Prognosis
