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嗜麦芽窄食单胞菌呼吸道感染耐药性分析

Analysis of Drug Resistance of Stenotrophomonas Maltophilia in Patients with Respiratory Infections
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摘要 目的:分析我院2008~2009年呼吸科嗜麦芽窄食单胞菌感染患者病原菌的耐药性及抗菌药物的选择,为合理应用抗菌药物提供依据。方法:对20例感染嗜麦芽窄食单胞菌的呼吸科住院患者药敏结果进行临床分析。结果:20株嗜麦芽窄食单胞菌对左氧氟沙星、哌拉西林/他唑巴坦等敏感率较高,对亚胺培南、氨曲南100%耐药。结论:高龄、严重基础疾病、侵入性操作等是嗜麦芽窄食单胞菌呼吸道感染的高危因素,根据药敏试验结果选择抗菌药物,减少易感因素,加强基础疾病的治疗,切断传播途径,避免交叉感染,是治疗和防止嗜麦芽窄食单胞菌感染的重要措施。 OBJECTIVE:To analyze the antibiotic resistance of stenotrophomonas maltophilia and the choice of antibiotics in patients with respiratory infection in our hospital from 2008 to 2009 to provide reference for rational use of antibiotics.METHODS:Clinical analysis on the drug susceptibility in 20 stenotrophomonas maltophilia respiratory infection cases was performed.RESULTS:The 20 strains of Stenotrophomonas Maltophilia were sensitive to piperacillin /tazobactam but completely resistant to imipenem and aztreonam,with resistance rates being 100%.CONCLUSION:Older age,underlying diseases and invasive procedures are high risk factors of stenotrophomonas maltophilia respiratory infections.To prevent and treat stenotrophomonas maltophilia respiratory infections,it is necessary to use antibiotics based on the results of drug sensitivity test,reduce predisposing factors,strengthen treatment of underlying diseases,cutting off the route of transmission and avoid cross-infection.
出处 《中国医院用药评价与分析》 2010年第6期496-497,共2页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 嗜麦芽窄食单胞菌 呼吸道感染 药敏 抗菌药物 Stenotrophomonas maltophilia Respiratory infection Drug susceptibility Antibiotics
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