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热休克蛋白70的功能及其在寄生虫生长发育中的作用 被引量：4

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摘要 热休克蛋白(heat shock protein,HSP)也称应激蛋白,具有分子伴侣活性。外源性HSP70能被宿主抗原提呈细胞(antigen presenting cell,APC)识别,引起前炎症反应及获得性免疫应答,而自体HSP70则具有抗炎效应。在最近的研究中还发现HSP70具有佐剂功效,能增强机体对其他抗原肽的免疫应答反应。HSP70在寄生虫的生长发育过程中也起着重要作用。
作者 何思杰 吕志跃 吴忠道
机构地区 中山大学中山医学院寄生虫学教研室
出处 《热带医学杂志》 CAS 2010年第5期621-624,共4页 Journal of Tropical Medicine
基金 国家自然科学基金(No.30771888)
关键词 HSP70 功能 寄生虫 生长发育
分类号 R38 [医药卫生—医学寄生虫学]
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参考文献36

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共引文献22

同被引文献31

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  • 6Rebecca E. Smith, Terry W. Spithill, Robert N. Pike, et al.Fasciola hepatica and Fasciola gigantica: Cloning and characterization of 70 kDa heat-shock proteins reveals variation in HSP70 gene expression between parasite species recovered from sheep [ J ].Experimental Parasitology, 2008, 118(4) : 536-542.
  • 7王强,李勉,张龙现.热休克蛋白与寄生虫感染的关系[J].中国畜牧兽医,2009,36(6):133-136. 被引量：6
  • 8杨洁,吴忠道.热激蛋白70（HSP70）及血吸虫HSP70研究进展[J].国际医学寄生虫病杂志,2011,38(6):360-364. 被引量：5
  • 9李萍,李永哲.IgG亚类检测在相关疾病中的临床意义[J].中华检验医学杂志,2012,35(3):207-211. 被引量：13
  • 10俞小淙,吴观陵,吴宜琴,张耀娟,章子豪.日本血吸虫感染大鼠血清特异性IgG及IgG2a IgG2c同型水平的动态观察[J].中国血吸虫病防治杂志,2000,12(3):148-150. 被引量：14

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热带医学杂志
2010年 第5期

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