摘要
目的:探讨甲状腺单发结节三维超声定性诊断价值。方法:对128例甲状腺单发结节患者行三维超声检查,评价甲状腺结节的三维灰阶特征及三维血管的形态及分布特征,并与术后病理结果对照,利用受试者操作特征曲线(ROC)评估其诊断价值。结果:甲状腺良恶性结节在三维灰阶超声特征、结节内部三维血管形态及分布、结节周边三维血管形态特征差异有统计学意义(P<0.01)。以三维灰阶超声特征来诊断甲状腺结节良恶性,ROC曲线下面积为0.9218,诊断价值较高;以结节周围血管形态来鉴别结节良恶性,ROC曲线下面积为0.8131,诊断价值中等;以三维超声灰阶和血管三维能量图整体评价结节良恶性,ROC曲线下面积为0.9608,诊断价值最高。结论:三维超声成像能评价甲状腺结节的灰阶特征及结节内部及周边血管的形态及分布特征,可以提高甲状腺单发结节的鉴别诊断能力。
Objective：To evaluate the diagnostic value of three-dimensional ultrasonography in single thyroid nodule.Methods：128 patients with single thyroid nodule were examined with three-dimensional ultrasonography to assess the characters of gray-scale and blood vessel morphology and distribution of thyroid nodules in three-dimensional ultrasonography.The results were compared with post-operative pathological results.The diagnostic value of three-dimensional ultrasonography was evaluated using receiver operating characteristic（ROC） curve.Results：Three-dimensional ultrasonography showed significant difference in the characters of gray-scale;vascular morphology and distribution of inner and surrounding vessels in malignant thyroid nodules in comparison to benign lessions（P0.01）.Using characteristics of three-dimensional gray-scale ultrasound as criteria of malignant and benign thyroid nodules,the area under ROC curve was 0.9218,diagnostic performances was better.Using surrounding blood vessels of thyroid nodules as criteria,the area under ROC curve was 0.8131,diagnostic performances was moderate.Using the whole character of gray-scale and blood vessel morphology and distribution in three-dimensional ultrasound as criteria,the area under ROC curve was 0.9608,diagnostic performance was the best.Conclusions：Three-dimensional ultrasound imaging can evaluate the characters of gray-scale and blood vessel morphology and distribution of thyroid nodules,and improve the capability in differentiating between malignant and benign thyroid nodules.
出处
《中国临床医学影像杂志》
CAS
北大核心
2010年第1期13-16,共4页
Journal of China Clinic Medical Imaging
基金
上海市浦东新区卫生系统重点学科建设资助(PWZXK2007-02)
