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尿激酶静脉溶栓治疗早期心肌再梗塞和心肌梗塞延展临床分析

Analysis on treating early myocardial reinfarction and extension of myocardial infarction with intravenous urokinase
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摘要 目的:研究尿激酶静脉溶栓治疗早期心肌再梗塞和心肌梗塞延展的临床疗效。方法:13例早期心肌再梗塞和心肌梗塞延展的患者在诊断确定后,2小时内静滴尿激酶。溶栓前及溶栓后2小时内,每30分钟记录一次心电图,6~24小时内,每2小时测定一次CPK-MB、LDH、SGOT。结果:13例中再通11例,再通率为84.61%,1例轻度出血,1例溶栓6小时后出现低血压。结论:对心肌早期再梗塞和心肌梗塞延展患者,及早、足量应用尿激酶静脉溶栓后有较好的临床效果。 AIM:To investigate the efficacy of intravenous urokinase infusion in the treatment of patients with early myocardial reinfarction and extension of myocardial infarction. METHOD-.In 13 patients with early myocardial reinfarction and extension of infarction, urokinas was infused intravenously within 2 hours affer establishment of diagnosis. ECGs were recorded before and every 30 minutes after thrombolytic therapy up to 2 hours. Within 6 to 24 hours, CPK-Mb, LDH and SGOT were detected every 2 hours. RESULTS; In 11 of 13 patients, blood perfusion to the infarcted myocardium was resumed. The recanalization rate reached 84. 61%. Mild bleeding happened in 1 case and hypotension happened 6 hours after thrombolytic therapy in 1 case. CONCLUSION: Early administration and sufficient dose of intravenous urokinase is proved bcneficial to the patients with early myocardial reinfarction and extension of infarction.
出处 《上海医药》 CAS 1999年第1期18-20,共3页 Shanghai Medical & Pharmaceutical Journal
关键词 心肌梗塞 再梗塞 尿激酶 溶栓疗法 临床分析 Early myocardial infarction extension of myocardial infarction thrombolytic therapy
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