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骨髓间充质干细胞移植治疗大鼠大脑中动脉缺血再灌注的研究 被引量：1

Transplantation of marrow stromal cell for the treatment of ischemic stroke
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摘要 间充质干细胞(Mesenchymal stem cells,MSCs)用于治疗大鼠大脑中动脉缺血再灌注模型(middle cerebral arteryo cclusion,MCAO)能够获得明显的神经功能恢复。本文对MSCs移植途径、类型、数量、时间点以及作用机制进行了综述。 Transplantation of mesenchymal stem cells can significantinly improve the neurological fuction of rates with middle cerebral artery occlusion （MSCs）. In this view,we will address the key points of MSCs transplantation, such as type, quantity , time, and mechanisms.
作者 刘世民 张昆南
机构地区 江西省人民医院神经内科
出处 《中华脑血管病杂志（电子版）》 2010年第3期25-30,共6页 Chinese Journal of Cerebrovascular Diseases(Electronic Edition)
基金 十一五国家科技支撑计划资助项目(2008BAI68B03)
关键词 间充质干细胞 大脑中动脉缺血再灌注 细胞移植 MSCs MCAO Cell transplantation
分类号 R743.3 [医药卫生—神经病学与精神病学]
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参考文献37

  • 1Peter J,Andrew C,Stephen G,et al.Concise review:mesenchymal stromal cells:potential for cardiovascular repair.Stem Cells,2008,26(9):2201-2210.
  • 2Mark F,Alastair M,Stephen C,et al.Multilineage potential of adult human mesenchymal stem cells.Science 1999,284(5411):143-147.
  • 3E.Jones,D.McGonagle.Human bone marrow mesenchymal stem cells in vivo.Rheumatology,2008,47(2):126-131.
  • 4Anna Corcione,Federica Benvenuto,Elisa Ferretti,et al.Human mesenchymal stem cells modulate B-cell functions.Blood,2006,107(1):367-372.
  • 5Katarina Le Blanc,Ida Rasmusson,Berit Sundberg,et al.Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells.Lancet,2004,363(9419):1439-41.
  • 6Alma J,Willem E.Immunomodulatory properties of mesenchymal stromal cells.Blood,2007,110(10):3499-3506.
  • 7Dominici M,Le Blanc K,Mueller I,et al.Minimal criteria for defining multipotent mesenchymal stromal cells.The international society for cellular therapy position statement.Cytotherapy,2006,8(4):315-317.
  • 8Li Hong Shen,Yi Li,Jieli Chen,et al.One-year follow-up after bone marrow stromal cell treatment in middle-aged female rats with stroke.Stroke,2007,38(7):2150-2156.
  • 9Li Hong Shen,Yi Li,Jieli Chen,et al.Intracarotid transplantation of bone marrow stromal cells increases axon-myelin remodeling after stroke.Neuroscience,2006,137(2):393-399.
  • 10Y.Li,J.Chen,L.Wang,et al.Treatment of stroke in rat with intracarotid administration of marrow stromal cells.Neurology,2001,56(12):1666-1672.

二级参考文献39

  • 1各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量：33089
  • 2Eglitis MA,Dawson D,Park KW,et al.Targeting of marrow derived astrocytes to the ischemic brain.Neuroreport 1999;10(6):1289-1292.
  • 3Kopen GC,Prockop DJ,Phinney DG.Marrow stromal cells migrate throughout forebrain and cerebellum,and they differentiate into astrocytes after injection into neonatal mouse brains.Proc Natl Acad SciUSA 1999;96(19):10711-10716.
  • 4Li Y,Chopp M,Chen J,Wang L,et al.Intrastriatal transplantation of bone marrow nonhematopoietic cells improves functional recovery after stroke in adult mice.J Cereb Blood Flow Metab 2000;20(9):1311-1319.
  • 5Chen J,Li Y,Chopp M.Intracerebral transplantation of bone marrow with BDNF after MCAo in rat.Neuropharmacology 2000;39(5):711-716.
  • 6Lu D,Mahmood A,Wang L,et al.Adult bone marrow stromal cells administered intravenously to rats after traumatic brain injury migrate nto brain and improve neurological outcome.Neuroreport 2001;12(3):559-563.
  • 7Chen J,Li Y,Wang L,et al.Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemic in rats.Stroke 2001;32(4):1005-1011.
  • 8Li Y,Chen J,Chen XG,et al.Human marrow stromal cell therapy fortroke in rat:neurotrophins and functional recovery.Neurology 2002;59(4):514-523.
  • 9Chen X,Li Y,Wang L,et al.Ischemic rat brain extracts induce human marrow stromal cell growth factor production.Neuropathology 2002;22(4):275-279.
  • 10Lee J,Kuroda S,Shichinohe H,et al.Migration and differentiation of nuclear fluorescence-labeled bone marrow stromal cells after transplantation into cerebral infarct and spinal cord injury in mice.Neuropathology 2003;23(3):169-180.

共引文献30

同被引文献15

引证文献1

二级引证文献5

中华脑血管病杂志（电子版）
2010年 第3期

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