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脂溢性角化病的研究进展 被引量:8

Research Progress of Seborrheic Keratosis
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摘要 脂溢性角化病的发生可能与日晒、年龄、病毒感染、遗传等因素密切相关.它是角质形成细胞成熟迟缓所致的一种良性表皮肿瘤,其发病机理可能与角质形成细胞成熟迟缓和凋亡受阻、增殖旺盛及角化过度、色素代谢异常等分子生物学机制有关.大多临床诊断很容易,有时需要病理诊断的确定,皮肤镜的应用为诊断提供更多的方法.随着对脂溢性角化病研究的深入,治疗手段不断改进,逐渐向创伤小、瘢痕少、依从性好的方向发展. Seborrheic keratosis are closely related with the sun, age, viral infections or genetic factors. It is a benign skin tumor with the slow maturation of keratinocytes, of which pathogenesis may be associated with slow maturation of keratinocytes and apoptosis blocked, hyperproliferation, hyperkeratosis, pigment metabolism and other molecular biological abnormal mechanisms. Most of the clinical diagnosis is easy, but sometimes it is necessary to be determined by pathological diagnosis, Now the application of the skin mirror provides more ways to diagnose it. With the further research of seborrheic keratosis and improvement of treatment, it has gradually developed to be small trauma, scar less and compliance better.
作者 佟立 万桂杰
出处 《内蒙古民族大学学报(自然科学版)》 2010年第3期351-355,共5页 Journal of Inner Mongolia Minzu University:Natural Sciences
关键词 脂溢性角化病 病因学 细胞凋亡 Seborrheic keratosis Etiology Cell apoptosis
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参考文献36

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