摘要
目的探讨主动脉球囊反搏(intra-aortic balloon pumping,IABP)应用对急性重症病毒性心肌炎治疗效果影响。方法2007年1月~2010年1月前瞻性收集急性重症心肌炎患者共50例,其中男性35例,女性15例,年龄19~45岁,平均(28.26±4.95)岁。根据治疗时是否应用IABP分为IABP组与非IABP组,观察治疗前后患者动脉压、心率、尿量、肾功能、心功能变化,以及住院期间死亡率及住院时间。结果IABP组与非IABP组比较,IABP组平均压升高,心率降低,24小时尿量增加,肾功能(SCr、eGFR)改善、NT-proBNP明显降低、心功能改善,治疗前后两组各指标变化幅度有统计学差异。IABP组有2例死亡,非IABP组死亡11例,两组间死亡率比较差异具有统计学意义。IABP组平均住院天数为12.45±3.36天,而非IABP组平均住院天数为17.73±5.25天,两组间比较有统计学差异。结论在急性重症病毒性心肌炎伴泵功能不全患者治疗中,应用IABP能降低患者死亡率,改善患者预后。
Objective To investigate the effects of application of IABP on acute severe viral myocarditis with pump failure patients. Methods 50 patients were chosen from January 2007 to January 2010,including 35 male and 15 female and the average age was 28.26±4.95 years. The patients were divided into IABP group and non-IABP group according to whether applying of IABP or not. To observate changes of the patients' arterial pressure,heart rate,urine output,renal function,heart function before and after treatment. And to analysis the patients' hospital stay,hospital mortality. Results The patients' arterial pressure,heart rate,urine output,renal function,heart function were improved more in IABP group and there were significant different between IABP and non-IABP group. 2 patients died in IABP group while 11 patients died in non-IABP group,and there were significant different between these two groups. The hospitalization time was shorter in IABP group,and there was different between these two groups. Conclusion Application of IABP on acute severe viral myocarditis with pump failure patients will reduce mortality and improve patient outcomes.
出处
《中国现代医药杂志》
2010年第5期38-41,共4页
Modern Medicine Journal of China
关键词
心肌炎
主动脉球囊反搏
重症
Myocarditis Intra-aortic balloon pumping Severe