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前列腺癌危险因素配比病例对照研究 被引量:7

Case-control study of Risk Factors of Prostate Cancer
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摘要 为了解前列腺癌发病的影响因素对137例经组织病理学检查确诊的前列腺癌患者及其医院对照进行了1∶1配比调查,运用SAS软件对资料进行统计学分析。单因素分析结果显示夫妻分居、肝病史、丧偶或离异、吸烟、饮酒、职业性毒物接触史是前列腺癌发病的危险因素;体力锻炼是一项保护性因素;多因素分析结果显示前列腺癌危险因素(比值比,95%可信区间)有丧偶或离异(6.29,2.04—19.38)、肝病史(4.90,1.30—18.40)、夫妻分居(2.91,1.32—6.41);保护性因素有体力锻炼(0.38,0.20—0.72)。 To investigate the risk factors of prostate cancer, a hospital_based 1:1 matched case-control study was conducted for 137 patients with prostate cancer and their matched controls in Wuhan. Univariate analysis results showed that man and wife living apart, liver diseases, the widowed or divorced, cigarette smoking, alcohol drinking and occupational exposures to some poisons were risk factors and physical activity at leisure times was a protective factor of the disease. Multivariate logistic regression analysis results showed that the widowed or divorced liver diseases, man and wife living apart were the independent risk factors, while physical activity at leisure times was an important protective factor. The odds ratio (corresponding 95% confidence interval) was 6.29(2.04-19.38),4.90(1.30-18 40),2.91(1.32-6.41)and0.38(0.20_0.72),respectively. Ths results of the study provided a preliminary evidence for the prevention of prostate cancer
出处 《预防医学情报杂志》 CAS 1999年第1期8-9,共2页 Journal of Preventive Medicine Information
关键词 前列腺癌 危险因素 配比调查 prostate cancer risk factors case-control study
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