摘要
颅骨锁骨发育不全综合征是一种先天性全身骨骼发育不全性疾病,临床罕见,以锁骨发育不良、囟门闭合延迟、方颅、乳牙脱落延迟、恒牙迟萌或阻生、多生牙以及颌骨形态异常为主要临床特征。本文报告1例颅骨锁骨发育不全综合征家系,并结合相关文献,对该病的发病率、发病机制、临床表现、诊断及治疗进行讨论。
Cleidocranial dysplasia （CCD） is a well-documented rare congenital disorder of the bone characterized by clavicular hypoplasia or aplasia,delayed closure of cranial fontanels,brachycephalic skull,delayed exfoliation of primary dentition,delayed eruption of permanent teeth,and multiple supernumerary and morphologic abnormalities of the maxilla and mandible.In this paper,a case of cleidocranial dysplasia syndrome family was reported,and its incidence,pathogenesis,clinical features and methods of treatment were discussed by reviewing relevant literatures.
出处
《中国口腔颌面外科杂志》
CAS
2010年第3期282-286,共5页
China Journal of Oral and Maxillofacial Surgery
