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内皮祖细胞与缺血性脑血管病研究进展 被引量：3

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摘要 脑卒中是严重危害人类健康的疾病，其中缺血性脑卒中占了80％左右。3h超早期用组织型纤溶酶原激活剂（t-PA）溶栓，由于受时间窗及其本身溶栓成功率的限制，只有约2％～3％缺血性脑卒中患者得到了溶栓治疗，内皮祖细胞（endothelial progenitor cells，EPCs）的发现有可能为缺血性脑血管病的治疗提供一种全新的有希望的治疗方法。EPCs已经成功地在外周血、骨髓、
作者 朱江 刘煜敏
机构地区 武汉大学中南医院神经内科
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2010年第5期436-438,共3页 Chinese Journal of Geriatrics
基金 基金项目：国家自然科学基金（30470601）
关键词 缺血性脑血管病 内皮祖细胞 组织型纤溶酶原激活剂 缺血性脑卒中 溶栓治疗 脑卒中患者 CELLS 人类健康
分类号 R743.3 [医药卫生—神经病学与精神病学]
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参考文献30

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同被引文献44

  • 1许予明,谭颂,刘鸣,张苏明.脑血管疾病诊断与治疗临床指南[J].内科急危重症杂志,2005,11(5):243-245. 被引量：103
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  • 4Mihail H,Wolfgang Er,Peter CW, et al. Endothelial progeni- tor cells mobilization, differentiation,and homing [J]. Arte- rioscler Thromb Vasc Bio J, 2003,23 : 1185-1189.
  • 5Chu K, Jung KH, Lee ST, et al. Circulating endothelial pro- genitor cells as a new marker of endothelial dysfunction or re- pair in acute stroke[J]. Stroke, 2008,39 : 1441-1447.
  • 6Hristov M,Erl R,Weber PC. Endothelial progenitor cells mo- bilization, differentiation, and homing[J]. Arterioscler Thromb Vasc Biol,2003,23(7) : 1185-1189.
  • 7Sobrino T, Hurtado O, Moro MA, et aI. The increase of cir- culating endothelial progenitor cells after acute ischemic stroke is associated with good outcome [J]. Stroke, 2007,38:2759-2764.
  • 8Yip HK,Chang LT, Chang WN, et al. Level and value of cir- culating endothelial progenitor cells in patients after acute is- chemic stroke[J]. Stroke, 2008,39 (1) : 69-74.
  • 9Sobrino T, Hurtado O, Moro MA, et al. The increase of circu- lating endothelial progenitor cells after acute isehemic stroke is associated with good outcome [ J ]. Stroke, 2007, 38 : 2759- 2764.
  • 10Giraldi-Guimarares A, Rezende-Lima M, Bnmo FP, et al. Treatment with bone marrow mononuelear cells induces functional recovery and decreases neurodegeneration after sensorimotor cortical isehemia in rats[J]. Brain Res, 2009, 1266: 108-120.

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中华老年医学杂志
2010年 第5期

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