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改良解剖性大脑半球切除术治疗婴儿偏瘫伴顽固性癫痫的疗效观察 被引量:6

Curative effects of modified anatomic hemispherectomy on patients with infantile hemiplegia accompanied with intractable epilepsy
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摘要 目的探讨改良解剖性大脑半球切除术治疗婴儿偏瘫伴顽固性癫痫的效果。方法采用改良的解剖性大脑半球切除术治疗婴儿偏瘫伴顽固性癫痫患者27例,随访其临床效果并分析原因。结果术后25例患者癫痫发作停止,2例基本控制。术后患者行为异常改善,神经功能障碍无加重,康复期缩短,无远期合并症出现。结论改良的解剖性大脑半球切除术在理论和实践上更加合理,是治疗婴儿偏瘫伴顽固性癫痫的有效方法。 Objective To explore the curative effect of modified anatomic hemispherectomy on the patients with infantile hemiplegia accompanied with intractable epilepsy.Method The modified anatomic hemispherectomy was performed in 27 patients with infantile hemiplegia accompanied with intractable epilepsy.The curative effect were observed by following up from 11 months to 12 years(mean,6 years).Results The epilepsy was totally controlled in 25 patients and basically controlled in 2 patients.The abnormal behavior was improved and the disturbance of the nervous function was not worsened in all the patients.Conclusion The curative effect of the modified anatomic hemispherectomy,which is reasonable in the theory and practice,on the patients with infantile hemiplegia accompaned with intractable epilepsy is good.
出处 《中国临床神经外科杂志》 2010年第5期257-260,共4页 Chinese Journal of Clinical Neurosurgery
关键词 大脑半球切除术 婴儿 偏瘫 癫痫 Hemispherectomy Infantile hemiplegia Epilepsy Curative effect
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参考文献12

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二级参考文献8

  • 1陈炳桓,杨炯达,王宜崇,李清海,徐宇伦,张天明.改进的大脑半球切除术治疗伴顽固性癫痫的婴儿脑性偏瘫(附14例报告)[J].中华神经外科杂志,1989,5(2):107-110. 被引量:18
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  • 4Buonomano DV,Merzenich MM.Cortical plasticity:from synapses to maps[J].Annu Rev Neurosci,1998,21:149-186.
  • 5Bode S,Firestine A,Mathern GW,et al.Residual motor control and cortical representations of function following hemispherectomy:effects of etiology[J].Child Neurol,2005,20(1):64-75.
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