摘要
目的观察ＬＢＮＰ对２１ｄＨＤＴ－６°卧床模拟失重所致立位耐力不良的对抗效果。方法１２名健康男性青年志愿者，进行２１ｄＨＤＴ－６°卧床实验。随机分为对照组和下体负压组，每组６人。与对照组不同，下体负压组在最后一周，每天进行１ｈ、－４．０ｋＰａ的下体负压锻炼。结果卧床前，１２名受试者顺利通过７５°、２０ｍｉｎ立位耐力检查。卧床第１０ｄ立位耐力检查时，对照组有５人、ＬＢＮＰ组有４人出现晕厥前或晕厥症状，两组平均耐受时间均低于卧床前（Ｐ＜０．０５）；第２１ｄ时，对照组有５人未通过，平均耐受时间较卧床前显著降低（Ｐ＜０．０５）；而ＬＢＮＰ组有１人未通过，平均耐受时间显著高于对照组（Ｐ＜０．０５）。结论２１ｄ头低位卧床后立位耐力显著降低。下体负压能够有效对抗头低位卧床导致的立位耐力降低。
Objective To investigate whether LBNP during 21 d -6°head down tilt(HDT) would modify
orthostatic tolerance. Method 12 healthy males, age 23.7±5.0, were exposed to -6° HDT for
21 d. 6 of them received -4.0 kPa LBNP sessions for 1h/d from 15 th day to 21 st day of HDT.
The other 6 served as control.HUT +75°,20 min orthostatic tolerance test were done before,on
day 10 and on day 21 of HDT. Result During HUT +75°,20 min orthostatic tolerance test on day
10 of HDT, 5 subjects of the control group and 4 of the LBNP group presented presyncopal or
syncopal signs and symptoms,the average standing time of both groups were shorter than
those of the pre HDT (P< 0.05 ).During HUT +75°,20 min orthostatic tolerance test on day 21
of HDT,5 subjects of the control group and one subject of the LBNP group presented
presyncopal or syncopal signs and symptoms, the average standing time of control group
reduced significantly as compared with those of pre HDT(P<0.05),also significantly shorter than
those of LBNP group (P<0.05). Conclusion The present study clearly shows that the use of
LBNP could alleviate the bed rest induced orthostatic intolerance.
出处
《航天医学与医学工程》
CAS
CSCD
1999年第2期97-100,共4页
Space Medicine & Medical Engineering
基金
863资助
关键词
下体负压
模拟失重
立位耐力
对抗效果
lower body
negative pressure
simulated weightlessness
orthostatic tolerance
